What if FAIR principles could extend beyond datasets to the workflows that transform raw data into knowledge? Learn how a FAIR end-to-end metagenomics workflow can support reproducibility, interoperability, and traceable data analysis.
Latest articles about UNLOCK
What if FAIR principles could extend beyond datasets to the workflows that transform raw data into knowledge? Learn how a FAIR end-to-end metagenomics workflow can support reproducibility, interoperability, and traceable data analysis.
In this edition, we spoke with Weishen Zeng, whose research focuses on the biological recycling of biodegradable plastic waste through anaerobic fermentation. Using the UNLOCK Modular Bioreactor, Biodiscovery and FAIR Data Platforms, the research investigates how biodegradable plastics can be converted into valuable carboxylic acids, while exploring the microbial communities involved and how the fermentation process can be monitored and better controlled.
In this edition, we spoke with Emmelie Joe Freudenberg Rasmussen, whose research focuses on understanding microbial interactions in the gut microbiome. Using the UNLOCK Biodiscovery platform, the study investigates how riboflavin supplied by an overproducing 𝘓𝘢𝘤𝘵𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘭𝘢𝘤𝘵𝘪𝘴 strain can support the growth of riboflavin-dependent 𝘍𝘢𝘦𝘤𝘢𝘭𝘪𝘣𝘢𝘤𝘵𝘦𝘳𝘪𝘶𝘮, providing new insights into microbial cross-feeding under oxygenated gut conditions.
Why is fermentation data often hard to reuse and reproduce? Learn how standards like MIFE and MIFD enable FAIR-by-design practices, improving data sharing, validation, and long-term reuse.
In this edition, we spoke with Silvana Inés Quiton Tapia, whose research investigates how dissolved organic carbon (DOC) influences microbial activity in groundwater. Using the UNLOCK Modular Bioreactor Platform, the study explores how DOC conditions shape metabolic strategies and micropollutant biotransformation.
In this feature, we spoke with Natalia Nadal Alemany, whose research explores the metabolic flexibility of the fermentative microorganism Clostridium pasteurianum. Using the UNLOCK Parallel Cultivation Platform, the study examines metabolic adaptation to iron limitation during anaerobic fermentation.
How do we ensure that research results are transparent, reproducible, and reusable? Learn how end-to-end FAIR-by-design approaches offer a powerful way to improve transparency, reproducibility, and long-term reuse of microbial omics data.
As part of our ongoing series showcasing researchers using UNLOCK’s research facilities, we spoke with Jinsong, a researcher conducting bioreactor-based research on microbial enrichment for biopolymer production using the UNLOCK Parallel Cultivation Platform.
How can microorganisms be guided to convert waste streams into valuable products, and which biological and operational factors determine these conversions? - an interview with the Manager of UNLOCK's Modular Bioreactor Platform David Strik
As part of our series highlighting users of UNLOCK’s research facilities, we spoke with Banchiamlak, a PhD researcher studying how chemical stressors and temperature change shape freshwater ecosystems. Her work combines whole-ecosystem experimentation with in-depth molecular analysis, made possible through the UNLOCK Biodiscovery and FAIR Data Platforms.
Want to monitor how your culture is performing in real time? Learn how advanced tools like BioLector XT and Nanopore sequencing with the help of the Biodiscovery Platform unlock new biotechnology breakthroughs.
What are the strings to pull to steer fermentation processes in such in way that they deliver exactly the desired products?- an interview with the Manager of UNLOCK's Parallel Cultivation Platform Robbert Kleerebezem
We are thrilled to introduce Martha Endika, our newest addition to the research team!
Can microbes break down bioplastics anaerobically—and even turn them into valuable products? Dr. Anca Delgado and WUR student David Jordens took on this challenge using UNLOCK’s powerful infrastructure, and the results are full of promise.
We are thrilled to introduce Tamara Hube Escare, our newest addition to the research team!
We are thrilled to introduce Alejandra Alonso Santirso, our newest addition to the research team!
Endosymbiotic bacteria live in symbiosis within other organisms. While they can be beneficial to their hosts, some are also capable of causing serious harm.
We are thrilled to introduce Emilie Alaux, our newest addition to the research team!
Syngas fermentation is a promising approach for converting industrial waste gases into valuable biochemicals. In this study, we developed iSJ444, the first genome-scale metabolic model for Clostridium luticellarii, a lesser-known but highly promising syngas-fermenting bacterium. Our model predicts how this microbe can convert syngas into valuable short-chain fatty acids, providing insights into its metabolic pathways and potential for industrial applications.
In modern farming, piglets are separated from their mother at an early age. This ‘weaning’ makes the animals vulnerable to all kinds of infectious diseases. It is a known fact that microorganisms play an important role in that process.
With a background in Food Technology and Human Nutrition, it might seem surprising that I found my way into the field of microbiology. My journey began after completing my PhD when I developed a strong interest in the associations between diet, gut microbiome, and health.
The Parallel Cultivation Platform offers an innovative approach to studying microbial communities under controlled conditions. This case study highlights the experiences of Rifki Wahyu Kurnianto, a PhD candidate at Delft University of Technology, as he utilized the platform to investigate the role of magnetite in anaerobic phenol degradation.
We are thrilled to introduce Xiaofang Yan, our newest addition to the research team! Xiaofang brings a wealth of knowledge and expertise that will undoubtedly enhance our projects and drive innovation.
Hello! My name is Peter van Nes, and since December 2024, I have been a technician at the Modular Bioreactor Platform. I hold a master's degree in Biotechnology from Wageningen University.
We are excited to welcome Martijn Melissen to our research team at SSB and UNLOCK! In this article, he introduces himself and shares his vision for his role.
UNLOCK has expanded its technological offerings with the Introduction of the MicroWriter ML3 Pro, an advanced and compact photolithography system that opens new possibilities for precision patterning in applications such as microfluidics, MEMS, and advanced micro-optical devices.
This landmark study, spearheaded by Andrea Dell’Olio and supervised by Josep Rubert from the Food Quality and Design and Nutritional Biology (division of human nutrition and health) chair groups at Wageningen University
Our latest research, published in The ISME Journal, introduces BIG-Syc, a synthetic infant gut microbial community. This groundbreaking model sheds light on the complex interactions within infant gut microbiota driven by human milk oligosaccharides (HMOs)
The UNLOCK 2nd annual Symposium proved to be a resounding success, filled with energy, knowledge sharing, and a collective drive for innovation. Participants were not only inspired by the diverse presentations and workshops but also by the vibrant community that UNLOCK has cultivated.
The current development state of the software and hardware projects within the Parallel Cultivation Platform was shown.
This publication represents the culmination of several years of work and is part of an ongoing community effort to update the genome-scale model (GEM) of S. cerevisiae, an industrial workhorse organism. The Yeast9 model is the latest consensus model, following the previous update published in 2019 (Yeast8).
Get to know our team and the unique features of the UNLOCK research facilities in Wageningen and Delft.
We are thrilled to invite you to the first UNLOCK symposium. Register now for free!
Will you be our new team member? Check out this vacancy at the UNLOCK bioreactor cultivation facility in the TU Delft laboratory.
Researchers from our FAIR Data Platform published a paper on the FAIR Data Station: A platform that helps you to manage your research metadata according to the FAIR principles.
On November 3rd, UNLOCK officially unlocked its facilities.
Our research platforms have different ways to identify new talent, but they are complementary and have one thing in common: They generate data. These data are taken care of by the FAIR Data platform.
Recently, UNLOCK-scientists composed a synthetic community of ten key microbes from the human intestinal tract: The Diet-based Minimal Microiobome.
Finally, in this third part of our blog series on our FAIR Data Station, we describe how you can build your own Semantic database
Previously, we introduced you to our FAIR Data Station. In this second part, we answer the question: Why even bother?
In a three-piece blog series, we guide you through the concept of our FAIR Data Station. First, in this blog, we explain how to get started.
Based on research projects and publications on microbiomes, researchers recently concluded that a systems approach is needed to fully unlock the potential of microbiomes.
September 17th is International Microorganism Day. For this reason, we explain the definition of microorganism and how you can contribute to IMD.
Today is World Microbiome Day 2021, on which we celebrate all microbes all around the world. It's also the day on which we officially UNLOCK our new website.
